High-performance liquid chromatographic preparation of oxybutynin enantiomers on a chiral stationary phase
β Scribed by Etsuko Miyamoto; Yoko Demizu; Yoshifumi Murata; Yutaka Yamada; Susumu Kawashima; Hitoshi Kontani; Takeshi Sakai
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 229 KB
- Volume
- 653
- Category
- Article
- ISSN
- 1873-3778
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Enantiomers of terfenadine were resolved by high-performance liquid chromatography (HF'LC) using a chiral stationary phase (CSP) column packed with p-cyclodextrin (p-CD) covalently bound to silica. Separation was achieved in both the reverse phase and normal phase modes. Resolution of enantiomers wa