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High-performance liquid chromatographic method for the quantitation of quinidine and selected quinidine metabolites

✍ Scribed by G.L. Hoyer; D.C. Clawson; L.A. Brookshier; P.E. Nolan; F.I. Marcus


Publisher
Elsevier Science
Year
1991
Weight
892 KB
Volume
572
Category
Article
ISSN
0378-4347

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The application of high-performance liquid chromatography to resolve the individual alkaloids present in marketed Cinchona alkaloids was investigated. Normal-phase and several reversed-phase systems were evaluated. The proposed procedure uses an alkylphenyl column; it adequately resolves quinidine,