A method for the determination of N-glucuronidation of nicotine and cotinine in human liver microsomes by high-performance liquid chromatography was developed. Nicotine or cotinine was incubated with human liver microsomes and UDP-glucuronic acid in a 200-l incubation mixture. The nicotine Nglucuron
✦ LIBER ✦
High-performance liquid chromatographic enantioselective assay for the measurement of ketoprofen glucuronidation by liver microsomes
✍ Scribed by Saïd Chakir; Marie-Hélène Maurice; Jacques Magdalou; Pierre Leroy; Nathalie Dubois; Françoise Lapicque; Zaïd Abdelhamid; Alain Nicolas
- Publisher
- Elsevier Science
- Year
- 1994
- Weight
- 431 KB
- Volume
- 654
- Category
- Article
- ISSN
- 0378-4347
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