A method for the determination of N-glucuronidation of nicotine and cotinine in human liver microsomes by high-performance liquid chromatography was developed. Nicotine or cotinine was incubated with human liver microsomes and UDP-glucuronic acid in a 200-l incubation mixture. The nicotine Nglucuron
β¦ LIBER β¦
High-performance liquid chromatographic assay for amiodarone N-deethylation in microsomes of rat liver
β Scribed by J.M. Trivier; J. Pommery; C. Libersa; J. Caron; M. Lhermitte
- Publisher
- Elsevier Science
- Year
- 1992
- Weight
- 624 KB
- Volume
- 579
- Category
- Article
- ISSN
- 0378-4347
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