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High-performance liquid chromatographic determination of mianserin in plasma and brain and its application to pharmacokinetic studies in the rat

โœ Scribed by Kouichi Kurata; Masayoshi Kurachi; Yasuyuki Tanii

Publisher
Elsevier Science
Year
1988
Weight
286 KB
Volume
434
Category
Article
ISSN
0378-4347

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## Abstract A simple, specific and sensitive HPLC method with UV detection was developed and validated for the determination of tectoridin in rat plasma for the first time. Chromatographic separation was performed on a Welchrom^TM^ C~18~ column (150 ร— 4.6ย mm, i.d., 5ย ยตm) at a flow rate of 1.0ย mLย mi