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High-performance liquid chromatographic determination of desmosine and isodesmosine in tissues and its application to studies of alteration of elastin induced by atherosclerosis

✍ Scribed by Yu Yamaguchi; Jun Haginaka; Masaru Kunitomo; Hiroyuki Yasuda; Yoshio Bandô


Book ID
107996640
Publisher
Elsevier Science
Year
1987
Weight
510 KB
Volume
422
Category
Article
ISSN
0378-4347

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High-performance liquid chromatographic
✍ Norman T. Soskel 📂 Article 📅 1987 🏛 Elsevier Science 🌐 English ⚖ 486 KB

Quantitation of desmosine and isodesmosine, the major crosslinks in elastin, has been of interest because of their uniqueness and use as markers of that protein. Accurate measurement of these crosslinks may allow determination of elastin degradation in vivo and elastin content in tissues, obviating