๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

High-performance liquid chromatographic assay of human red blood cell thiopurine methyltransferase activity

โœ Scribed by Lynne Lennard; Helen J. Singleton

Book ID
103805183
Publisher
Elsevier Science
Year
1994
Weight
710 KB
Volume
661
Category
Article
ISSN
0378-4347

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Segregation analysis of human red blood
Segregation analysis of human red blood cell thiopurine methyltransferase activity
โœ John P. Vuchetich; Richard M. Weinshilboum; Dr. R. Arlen Price ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 670 KB

Thiopurine methyltransferase (TPMT) catalyzes thiopurine S-methylation, an important metabolic pathway for drugs such as 6-mercaptopurine (6-MP). Inherited differences in the activity of this enzyme are related to individual differences in the therapeutic efficacy and toxicity of 6-MP and other thio

A rapid and sensitive high-performance l
A rapid and sensitive high-performance liquid chromatographic assay for 6-mercaptopurine metabolites in red blood cells
โœ Lawrence E. Lavi; John S. Holcenberg ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 635 KB

A highly sensitive and rapid assay for the detection of 6-mercaptopurine metabolites in the red blood cells-of leukemic patients receiving the drug has been developed. The method employs a batchchromatographic procedure using a mercurial cellulose resin to selectively absorb thiol compounds combined