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High Level Expression of Tissue-Nonspecific Alkaline Phosphatase in the Milk of Transgenic Rabbits

✍ Scribed by L. Bodrogi; R. Brands; W. Raaben; W. Seinen; M. Baranyi; D. Fiechter; Zs Bősze

Publisher
Springer Netherlands
Year
2006
Tongue
English
Weight
336 KB
Volume
15
Category
Article
ISSN
0962-8819

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Hypophosphatasia is a rare inherited disorder characterized by defective bone mineralization and deficiency of serum and tissue liver/bone/kidney tissue alkaline phosphatase (L/B/K ALP) activity. We report here the characterization of tissue-nonspecific alkaline phosphatase (TNSALP) gene mutations i