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High-Level Expression of Human Thymidylate Synthase

โœ Scribed by Joan Pedersen-Lane; Gladys F. Maley; Edward Chu; Frank Maley

Book ID
115645186
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
208 KB
Volume
10
Category
Article
ISSN
1046-5928

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Posttranscriptional regulation of thymid
Posttranscriptional regulation of thymidylate synthase gene expression
โœ Lee F. Johnson ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 619 KB

Thymidylate synthase (TS) is an essential enzyme that catalyzes the formation of thymidylic acid in the de novo biosynthetic pathway and i s the target enzyme for a variety of chemotherapeutic agents. The TS gene is expressed at a much higher level in proliferating cells than in quiescent cells. Con