High level expression of human apolipoprotein A-I in transgenic rats raises total serum high density lipoprotein cholesterol and lowers rat apolipoprotein A-I
✍ Scribed by Marke E. Swanson; Thomas E. Hughes; Irene St Denny; Dennis S. France; James R. Paterniti; Carlo Tapparelli; Patrick Gfeller; Kurt Bürki
- Book ID
- 110549387
- Publisher
- Springer Netherlands
- Year
- 1992
- Tongue
- English
- Weight
- 902 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0962-8819
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📜 SIMILAR VOLUMES
Capillary gel electrophoresis was performed on a coated capillary column filled with a replaceable low-viscosity polymer network containing sodium dodecyl sulfate (eCAP SDS-200 kit from Beckman Instruments). While apolipoprotein (apo) A-I gave an homogeneous peak in high-density lipoprotein (HDL), i
## Abstract ## Background Inherited apolipoprotein (Apo) A‐I deficiency is an orphan disorder characterized by high‐density lipoprotein (HDL)‐cholesterol deficiency and premature atherosclerosis. Constitutive over‐expression of ApoA‐I might provide a means to treat this disease. The present study