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High glucose activates the Wnt/β-catenin pathway and reduces matrix mineralization in human osteoblastic cells

✍ Scribed by N. Garcia-Giralt⁎; R. Urreizti; G. Yoskivitz; N. Cols; R. Güerri; P. Sarrion; S. Balcells; L. Mellibovsky; X. Nogues; D. Grinberg; P. Esbrit; A. Diez-Perez


Book ID
116325343
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
191 KB
Volume
50
Category
Article
ISSN
8756-3282

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IGFBP-4 activates the Wnt/beta-catenin s
✍ Koji Ueno; Hiroshi Hirata; Shahana Majid; Z. Laura Tabatabai; Yuji Hinoda; Rajvi 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 772 KB

## Abstract The Wnt/β‐catenin signaling pathway is inactivated by Wnt antagonists in most cancers and IGFBP‐4 is an antagonist of the Wnt/ β‐catenin signaling pathway. However, the function of IGFBP‐4 is not currently understood in renal cell carcinoma (RCC). We initially found that the expression