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High frequency ofBRCA1/2andp53somatic inactivation in sporadic ovarian cancer

✍ Scribed by Michal Zikan; Marketa Janatova; David Pavlista; Petr Pohlreich


Book ID
107584977
Publisher
Indian Academy of Sciences
Year
2007
Tongue
English
Weight
76 KB
Volume
86
Category
Article
ISSN
0022-1333

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## Abstract Breast cancer occurs rarely in men and risk factors for the disease include germline mutations of the __BRCA2__ gene. High frequency of allelic loss at the __BRCA2__ locus has been reported in sporadic breast tumors, but somatic mutations of __BRCA2__ are very rare. Here we report the f