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High frequency of mutation to tubercidin resistance in CHO cells

✍ Scribed by Michael S. Rabin; Michael M. Gottesman

Book ID
112559312
Publisher
Springer
Year
1979
Tongue
English
Weight
641 KB
Volume
5
Category
Article
ISSN
1572-9931

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Reduced permeability in CHO cells as a m
Reduced permeability in CHO cells as a mechanism of resistance to colchicine
✍ Dr. Victor Ling; Larry H. Thompson πŸ“‚ Article πŸ“… 1974 πŸ› John Wiley and Sons 🌐 English βš– 1015 KB

## Abstract Colchicine resistant (CH^R^) lines of stable phenotype have been isolated from cultured Chinese hamster (CHO) cells. Successive single‐step selections for increasing resistance were performed by isolating resistant colonies at each step. Two complementary assays involving [^3^H] colchic