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High-frequency minisatellite instability of the mitochondrial genome in colorectal cancer tissue associated with clinicopathological values

✍ Scribed by Sang Woo Lim; Hye Ran Kim; Hwan Young Kim; Jung Wook Huh; Young Jin Kim; Jong Hee Shin; Soon Pal Suh; Dong Wook Ryang; Hyeong Rok Kim; Myung Geun Shin


Book ID
112101696
Publisher
John Wiley and Sons
Year
2012
Tongue
French
Weight
410 KB
Volume
131
Category
Article
ISSN
0020-7136

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## Abstract High‐frequency microsatellite instability (MSI‐H) due to defective DNA mismatch repair occurs in the majority of hereditary nonpolyposis colorectal cancers (HNPCCs) and in a subset of sporadic malignant tumors. Clinicopathologic and genotypic features of MSI‐H colorectal tumors in HNPCC