Successful in vivo NMR spectroscopy requires a combination of techniques to address the problems of volume selection, water suppression, and resolution. All this needs to be done in the very heterogeneous environment found in living organisms. Previously published techniques are used to obtain 'H sp
High-field localized in vivo proton spectroscopy on micro volumes
✍ Scribed by David M. Doddrell; James Field; Stuart Crozier; Ian M. Brereton; Graham J. Galloway; Stephen E. Rose
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 311 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0740-3194
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✦ Synopsis
Abstract
A water‐suppressed volume‐selected in vivo ^1^H spectrum of 0.2 ml of a rat brain has been obtained at 200 MHz using the SPACE localization method. Good signal‐to‐noise and spectral resolution were obtained by averaging 256 acquisitions. The spectrum shows little T~2~ weighting effect.
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