High field 1H NMR studies. Influence of the cis/trans isomerism on the N-acetyl 4-hydroxy proline ring conformation

Assignments of the 1H and 13C NMR spectr

Assignments of the 1H and 13C NMR spectra of trans-4-hydroxy-N-9-fluorenylmethoxycarbonyl-L-proline using one- and two-dimensional NMR spectroscopy

✍ Dagfinn W. Aksnes; George W. Francis; Dionissios Papaioannou 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 161 KB

## Abstract The ^1^H and ^13^C NMR spectra of __trans__‐4‐hydroxy‐__N__‐9‐fluorenylmethoxycarbonyl‐L‐proline show a 56:44 mixture of two conformers due to hindered rotation around the partial CN double bond. A combination of homo‐ and heteronuclear 1 D and 2D NMR techniques provided the assignment