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High Expression of Thymidylate Synthase Leads to Resistance to 5-Fluorouracil in Biliary Tract Carcinomain vitro

โœ Scribed by Habara, Kazuto ;Ajiki, Tetsuo ;Kamigaki, Takashi ;Nakamura, Takeshi ;Kuroda, Yoshikazu


Book ID
108581985
Publisher
Wiley (Blackwell Publishing)
Year
2001
Tongue
English
Weight
67 KB
Volume
92
Category
Article
ISSN
0910-5050

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High expression of thymidylate synthase
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## Background: In the past 4 years, the weekly 24-hour infusion of high dose 5-fluorouracil (5-fu) and leucovorin in the treatment of patients with advanced gastric carcinoma has been prospectively studied at the authors' institution. this has enabled them to explore the possibility that the level