High expression of lymphocyte surface immunoglobulin in chronic lymphocytic leukaemia may be a bad prognostic sign
โ Scribed by Berntorp, Erik ;Zettervall, Olle
- Book ID
- 114790426
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Weight
- 431 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0036-553X
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## Abstract ## Background: Increased CD38 expression by leukemic cells has been suggested as an adverse prognostic factor in BโCLL. Several approaches have been proposed to quantify its level of expression by flow cytometry. ## Methods: We compared the use of (i) the percentage of CD38 positive
## Abstract We have previously identified 12 surface antigens whose differential expression represented the signature of Bโcell chronic lymphocytic leukemia (BโCLL) subsets with different prognosis. In the present study, expression data for these antigens, as determined in 137 BโCLL cases, all with