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Heterogeneous intracellular expression of B-cell receptor components in B-cell chronic lymphocytic leukaemia (B-CLL) cells and effects of CD79b gene transfer on surface immunoglobulin levels in a B-CLL-derived cell line

✍ Scribed by Sonia Minuzzo; Stefano Indraccolo; Valeria Tosello; Erich Piovan; Anna Cabrelle; Livio Trentin; Giampietro Semenzato; Alberto Amadori

Book ID
108673386
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
389 KB
Volume
130
Category
Article
ISSN
0007-1048

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## Abstract ## Background: Increased CD38 expression by leukemic cells has been suggested as an adverse prognostic factor in B‐CLL. Several approaches have been proposed to quantify its level of expression by flow cytometry. ## Methods: We compared the use of (i) the percentage of CD38 positive