High-dose loperamide in the treatment of 5-fluorouracil-induced diarrhea in colorectal cancer patients
β Scribed by S. Cascinu; E. Bichisao; D. Amadori; V. Silingardi; P. Giordani; E. Sansoni; G. Luppi; V. Catalano; R. Agostinelli; G. Catalano
- Publisher
- Springer-Verlag
- Year
- 2000
- Tongue
- English
- Weight
- 41 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0941-4355
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Background. In a previous Phase I1 trial, the authors showed that a weekly continuous infusion of 5-fluorouracil (5-FU) at a dose of 3.5 g/mz for 48 hours is an active treatment for advanced colorectal cancer. The overall response rate was 38.5%, and the median survival was 12 months. These data wer
with low dose LV. Based on these reports, a first-line Phase II study was performed in 101 patients with advanced colorectal carcinoma who were given a bimonthly