High Dose Intravenous IgG Reduces Platelet Associated Immunoglobulins and Complement in Idiopathic Thrombocytopenic Purpura
✍ Scribed by Winiarski, Jacek ;Kreuger, Anders ;Ejderhamn, Jan ;Holm, Göran
- Book ID
- 114789871
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Weight
- 366 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0036-553X
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Sixteen adult patients of mean age 48 years with chronic ITP were studied for platelet response to high-dose (0.4 g/kg body weight per day for five consecutive days) intravenous polyvalent intact IgG in the absence of any concurrent treatment. The platelet count returned to normal values in nine pat
Ten adult patient of chronic idiopathic thrombocytopenic purpura (CITP) used oral prednisone and were treated with seven doses of oral high-dose methylprednisolone (30 mg/kg). Nine of ten patients responded after HDMP treatment (plt > 150 × 10 9 /L). Two patients having 8 and 10 years of history ach