The chemotherapeutic treatment of recurrent and/or metastatic squamous cell carcinoma (SCC) of the head and neck (H & N) has a very dismal prognosis, with survival usually not exceeding 1 year. Reported objective response rates vary between 3% and 70%. This difference appears largely attributable to
High-dose cisplatin for locally advanced or metastatic head and neck cancer. A phase ii pilot study
โ Scribed by Kathleen A. Havlin; John G. Kuhn; J. William Myers; Robert F. Ozols; Douglas E. Mattox; Gary M. Clark; Daniel D. Von Hoff
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 484 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Background: Induction chemotherapy in locoregionally advanced squamous cell carcinoma of the head and neck (scchn) might improve survival with respect to radiation therapy alone. furthermore, chemotherapy represents the only therapeutic option in metastatic head and neck carcinoma. ## Methods:
## Background: A previous southwest oncology group study demonstrated a 30% response rate with the combination of cisplatin and mitotane in the treatment of patients with metastatic adrenocortical carcinoma. several case reports suggested that the combination of etoposide and cisplatin may be an ac