High-dose cisplatin and VP-16 with bleomycin, in the management of advanced metastatic germ cell tumors
✍ Scribed by Daugaard, Gedske; Rørth, Mikael
- Book ID
- 122801823
- Publisher
- Elsevier Science
- Year
- 1986
- Weight
- 848 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0277-5379
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Most effective treatment regimens for advanced nonseminomatous testis tumors (NSIT) employ vinblastine (V), cisplatin (CDDP), and bleomycin (B) and adjunctive surgery. The toxicity of many of these multidrug programs, primarily from vinblastine-induced myelosuppression has resulted in significant pa
## Abstract A trial was undertaken to assess the efficacy and toxicity of high‐dose cisplatin and etoposide in children with newly diagnosed advanced malignant germ cell tumors. A total of eleven children and adolescents were treated with courses of high dose cisplatin 30 mg/m^2^/day and etoposide