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High-dose chemotherapy with autologous stem cell rescue for children with high risk and recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors

✍ Scribed by Antonio Pérez-Martínez; Alvaro Lassaletta; Marta González-Vicent; Julián Sevilla; Miguel Angel Díaz; Luis Madero


Publisher
Springer US
Year
2005
Tongue
English
Weight
266 KB
Volume
71
Category
Article
ISSN
0167-594X

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## Abstract ## BACKGROUND. High‐dose chemotherapy (HDCT) with autologous stem cell rescue (ASCR) has been reported to be effective in treating children with recurrent central nervous system (CNS) malignancies. ## METHODS. To evaluate the efficacy and toxicities of HDCT and ASCR, the medical reco

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## Abstract ## BACKGROUND The objective of the current study was to determine the outcome of children with local recurrence or progression of medulloblastoma in patients who received high‐dose chemotherapy (HDC) and posterior fossa (PF) irradiation. ## METHODS HDC consisted in busulfan at a dose