๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

High-dose chemotherapy for recurrent medulloblastoma : Time for a reappraisal

โœ Scribed by Amar Gajjar


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
45 KB
Volume
112
Category
Article
ISSN
0008-543X

No coin nor oath required. For personal study only.

โœฆ Synopsis


A stringently selected group of pediatric patients with recurrent medulloblastoma have been salvaged by highโ€dose chemotherapy. Based on the pediatric experience, the authors of the current study used a retrospective institutional series to demonstrate that adult patients with recurrent medulloblastoma who are treated with highโ€dose chemotherapy and autologous stem cell rescue enjoy a longer duration of disease control and overall survival than patients treated with standardโ€dose chemotherapy at the time of disease recurrence.


๐Ÿ“œ SIMILAR VOLUMES


High-dose chemotherapy with autologous s
โœ Vita Ridola; Jacques Grill; Francois Doz; Jean-Claude Gentet; Didier Frappaz; Ma ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 293 KB ๐Ÿ‘ 1 views

## Abstract ## BACKGROUND The objective of the current study was to determine the outcome of children with local recurrence or progression of medulloblastoma in patients who received highโ€dose chemotherapy (HDC) and posterior fossa (PF) irradiation. ## METHODS HDC consisted in busulfan at a dose

High-dose chemotherapy with autologous s
โœ Chie-Schin Shih; Gregory A. Hale; Lindsey Gronewold; Xin Tong; Fred H. Laningham ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 129 KB ๐Ÿ‘ 1 views

## Abstract ## BACKGROUND. Highโ€dose chemotherapy (HDCT) with autologous stem cell rescue (ASCR) has been reported to be effective in treating children with recurrent central nervous system (CNS) malignancies. ## METHODS. To evaluate the efficacy and toxicities of HDCT and ASCR, the medical reco

High time for low-dose prospective clini
โœ Robert S. DiPaola; Henry J. Durivage; Barton A. Kamen ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 49 KB

The article by Glode et al. in this issue reports on the empiric success, as defined by a decreased prostate specific antigen level and lack of toxicity, of metronomically delivered lowโ€dose chemotherapy for patients with hormoneโ€refractory prostate carcinoma. The data presented were collected as a

Intensive timed sequential remission ind
โœ Loeb, David M. ;Bowers, Daniel C. ;Civin, Curt I. ;Friedman, Alan D. ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 91 KB

## Background: Timed sequential chemotherapy and high-dose cytarabine (cytosine arabinoside, ara-c; hdac) are both effective treatments for acute myeloid leukemia (aml). we review our institutional experience with timed sequential induction chemotherapy consisting of daunorubicin/ara-c/-thioguanine