## Abstract ## BACKGROUND Preclinical and clinical data have suggested that highโdose calcitriol (1,25โdihydroxycholecalciferol) has activity against prostate carcinoma. Pulseโdosed calcitriol and dexamethasone may maximize tolerability and efficacy. The authors examined the toxicity of pulseโdose
High-dose calcitriol, zoledronate, and dexamethasone for the treatment of progressive prostate carcinoma
โ Scribed by Kadri Altundag; Ozden Altundag; Paolo Morandi; Mehmet Gunduz
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 59 KB
- Volume
- 101
- Category
- Article
- ISSN
- 0008-543X
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An increased understanding of the biology of prostate carcinoma has led to the clinical evaluation of mechanism-based and targeted therapies. Modulating the immune system has been pursued through the use of both active and passive immunity as well as the ex vivo genetic manipulation of effector cell