Tau hyperphosphorylation in apolipoprote
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L. Genis; Y. Chen; E. Shohami; D.M. Michaelson
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Article
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2000
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John Wiley and Sons
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English
⚖ 133 KB
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Apolipoprotein E (apoE)-deficient mice have learning and memory impairments that are associated with specific neurochemical changes and hyperphosphorylation of distinct epitopes of the cytoskeletal protein tau. Furthermore, such mice are highly susceptible to the sequelae of brain trauma and their a