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High angle neutron fibre diffraction studies of the distribution of water around the D form of DNA

โœ Scribed by V.T. Forsyth; A. Mahendrasingan; P. Langan; Y. Al-Hayalee; D. Alexeev; W.J. Pigram; W. Fuller; S.A. Mason

Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
373 KB
Volume
180-181
Category
Article
ISSN
0921-4526

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โœฆ Synopsis

The instrument D19 at the Institut Laue-Langevin, Grenoble, has been used to undertake neutron fibre diffraction studies of the location of water around the D form of the DNA double helix. These studies clearly show the distribution of water in the small and large grooves of the molecule and, together with information from X-ray studies on the location of cations around the molecule, provide new information on the factors which help to stabilise this form of DNA.

๐Ÿ“œ SIMILAR VOLUMES

A neutron diffraction study of the distr
A neutron diffraction study of the distribution of water in the A form of the DNA double helix
โœ P. Langan; V.T. Forsyth; A. Mahendrasingam; D. Alexeev; W. Fuller; S.A. Mason ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 355 KB

High angle diffraction data from ordered fibres of DNA in the A form have been collected on diffractometer D19 at the Institute Laue-Langevin. By exploiting the ability to isotopically replace H,O surrounding the DNA by D,O we have been able to locate water around the double helix.