High-affinity uptake of taurine and β-alanine in primary cultures of rat astrocytes
✍ Scribed by I. Holopainen; Pirjo Kontro
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 446 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0364-3190
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Taurine uptake in cultured cerebellar granule cells and astrocytes consisted of a saturable high-affinity component and nonsaturable diffusion. The transport constant (Km) was significantly lower and the maximal velocity (V) higher in granule cells than in astrocytes. The uptakes were strictly sodiu
Uptake and oxidative metabolism of [I4C]malate as well as its incorporation into aspartate, glutamate, glutamine, and GABA were studied in cultured cerebral cortical neurons (GABAergic), cerebellar granule neurons (glutamatergic), and cerebral cortical astrocytes. All cell types exhibited high affin
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