✦ LIBER ✦

High-Affinity States of Human Brain Dopamine D2/3 Receptors Imaged by the Agonist [11C]-(+)-PHNO

✍ Scribed by Matthäus Willeit; Nathalie Ginovart; Shitij Kapur; Sylvain Houle; Doug Hussey; Philip Seeman; Alan A. Wilson

Book ID: 119197013
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 225 KB
Volume: 59
Category: Article
ISSN: 0006-3223
DOI: 10.1016/j.biopsych.2005.09.017

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Automated preparation of the dopamine D2

Automated preparation of the dopamine D2/3 receptor agonist ligand [11C]-(+)-PHNO for human PET imaging studies

✍ Christophe Plisson; Mickael Huiban; Sabina Pampols-Maso; Görkem Singleton; Samue 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 830 KB

In vitro characterisation of the high af

In vitro characterisation of the high affinity D2/D3 dopamine agonist (+)PhNO

✍ Christine Parker; K. Clarke; A.D. Gee; A. Gee; E. Rabiner 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 61 KB

Positron emission tomography quantificat

Positron emission tomography quantification of [11C]-(+)-PHNO binding to the dopamine D2/D3 receptors in the human brain

✍ Nathalie Ginovart; M. Willeit; P. Rusjan; A. Graff; I. Vitcu; P. Bloomfield; S. 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 56 KB

PET imaging of dopamine D3 receptors in

PET imaging of dopamine D3 receptors in humans with [11C]-(+)-PHNO: dissection of PHNO signal using two highly selective D3 antagonists

✍ Graham E. Searle; John D. Beaver; Laura E. Iavarone; Robert A. Comley; Massimo B 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 302 KB

Brain region binding of the D2/3 agonist

Brain region binding of the D2/3 agonist [11C]-(+)-PHNO and the D2/3 antagonist [11C]raclopride in healthy humans

✍ Ariel Graff-Guerrero; Matthaeus Willeit; Nathalie Ginovart; David Mamo; Romina M 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 412 KB

## Abstract The D~2~ receptors exist in either the high‐ or low‐affinity state with respect to agonists, and while agonists bind preferentially to the high‐affinity state, antagonists do not distinguish between the two states. [^11^C]‐(+)‐PHNO is a PET D~2~ __agonist__ radioligand and therefore pro

Binding characteristics and sensitivity

Binding characteristics and sensitivity to endogenous dopamine of [11C]-(+)-PHNO, a new agonist radiotracer for imaging the high-affinity state of D2 receptors in vivo using positron emission tomography

✍ Nathalie Ginovart; Laurent Galineau; Matthaeus Willeit; Romina Mizrahi; Peter M. 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 285 KB