A method tor the selection and isolation ot hexose transport mutants in unditterentiated rat myoblast L6 cells is reported; 2-deoxy-D-glucose (2-DOG)and 2-deoxy-2-fluoro-D-glucose (2FG)-resistant mutants were selected after mutagenization of L6 cells with ethyl methanesulfonate. Of these, D18 and D2
Hexose transport in L6 rat myoblasts. II. The effects of sulfhydryl reagents
β Scribed by Tony D'amore; Theodore C. Y. Lo
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 757 KB
- Volume
- 127
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
β¦ Synopsis
N6A 5C1
OMG was transported exclusively by the sulfhydryl reagent insensitive low affinity system (Christopher et al., 1976). In this manuscript, we report the effects of sulfhydryl reagents on hexose uptake in undifferentiated L6 rat myoblasts. As in the case with chick embryo fibroblasts, these reagents were found to inhibit the high
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