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Hexaprenoid Hydroquinones, Novel Inhibitors of the Reverse Transcriptase of Human Immunodeficiency Virus Type 1

✍ Scribed by Loya, Shoshana; Tal, Ruth; Hizi, Amnon; Issacs, Sara; Kashman, Yoel; Loya, Yossi


Book ID
125981517
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
369 KB
Volume
56
Category
Article
ISSN
0163-3864

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Inhibitory antibodies to the reverse transcriptase (RT) of human immunodeficiency virus type-1 (HIV-1) can be used to block the life cycle of the virus. We have isolated five different human single chain Fv (ScFv) antibodies specific for HIV-1 RT from an antibody phage display library. Three of thes