𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hexahydrophthalic acid in urine as an index of exposure to hexahydrophthalic anhydride

✍ Scribed by B. Jönsson; H. Welinder; G. Skarping

Publisher
Springer-Verlag
Year
1991
Tongue
English
Weight
268 KB
Volume
63
Category
Article
ISSN
0340-0131

No coin nor oath required. For personal study only.

✦ Synopsis

Post-shift and next-morning urine was sampled from workers exposed to hexahydrophtalic anhydride (HHPA), an epoxy hardener, sensitising at low exposure levels Exposure levels of HHPA in air gas chromatography, GC) in the range of 30-270 jig/m corresponded to urinary concentrations of 0 9-2 8 H mol hexahydrophthalic acid (HHP acid; GC-mass spectrometry)/mmol creatinine In the morning samples the concentrations were < O 04-0 3 mol HHP acid/mmol creatinine In unexposed controls, the level was < O 1 mol/mmol creatinine A correlation was found between the time-weighted levels of HHPA in air and HHP acid in the post-shift urine (rs = 0 93 ; P < O 023), indicating that the determination of HHP acid in urine is suitable for biologic monitoring of HHPA exposure.

📜 SIMILAR VOLUMES

8-Hydroxydeoxyguanosine in urine as an i
8-Hydroxydeoxyguanosine in urine as an index of oxidative damage to DNA in the evaluation of atopic dermatitis
✍ Tsuboi; Kouda; Takeuchi; Takigawa; Masamoto; Takeuchi; Ochi 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 353 KB

8-hydroxydeoxyguanosine (8-OHdG) is one of the products which are excreted in urine as a result of oxidative damage to DNA. We investigated the feasibility of using 8-OHdG in urine as an index for oxidative damage to DNA in atopic dermatitis (AD). Seventeen patients with long-standing AD and 17 heal

Speciation of Arsenic Compounds in the U
Speciation of Arsenic Compounds in the Urine of Rats Orally Exposed to Dimethylarsinic Acid Ion Chromatography with ICP–MS as an Element-Selective Detector
✍ Yoshinori Inoue; Yukiko Date; Kaoru Yoshida; Hua Chen; Ginji Endo 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 355 KB 👁 2 views

A combined ion chromatography (IC) with inductively coupled plasma mass spectrometry (ICP-MS) system as an element-selective detector has been used for the determination of arsenic compounds. Seven arsenic compounds were separated by cation-exchange chromatography. Subsequently, the separated arseni

Quantitative determination of hydroxy fa
Quantitative determination of hydroxy fatty acids as an indicator of in vivo lipid peroxidation: Oxidation products of arachidonic and docosapentaenoic acids in rat liver after exposure to carbon tetrachloride
✍ David W. Thomas; Frederik J.G.M. van Kuijk; Robert J. Stephens 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 628 KB

An improved gas chromatography-mass spectrometry method has been applied to the quantitation of both in vitro and in vivo products of lipid peroxidation in rat liver stimulated with carbon tetrachloride. The method avoids problems of autoxidation of unsaturated fatty acids during sample preparation,