TheE-linked subregion of the major histo
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Sachiko Hirose; Danqing Zhang; Shingo Nozawa; Hiroyuki Nishimura; Toshikazu Shir
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Article
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1994
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Springer-Verlag
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English
⚖ 339 KB
The NZB x NZW F1 mxce spontaneously develop autoimmune disease resembling human systemic lupus erythematosus (SLE). This disease is characterized by severe lupus nephritis, which develops in close association with the production of IgG class autoantibodies to double-stranded (ds) DNA and histones (S