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Does the deletion within T cell receptor β-chain gene of NZW mice contribute to autoimmunity in (NZB × NZW)F1mice?

✍ Scribed by Yusuke Yanagi; Sachiko Hirose; Ryuji Nagasawa; Toshikazu Shirai; Tak W. Mak; Tomio Tada


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
456 KB
Volume
16
Category
Article
ISSN
0014-2980

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Natural killer T (NKT) cells and CD5(+)B cells were searched for in various immune organs of autoimmune prone (NZBxNZW)F(1) (NZB/W F(1)) mice. The number of lymphocytes increased in the liver, spleen, and peritoneal cavity after the onset of disease (at the age of 30 weeks) while the number of thymo