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Differences between CD8+ T cells in lupus-prone (NZB × NZW) F1 mice and healthy (BALB/c × NZW) F1 mice may influence autoimmunity in the lupus model

✍ Scribed by George A. Karpouzas; Antonio La Cava; Fanny M. Ebling; Ram Raj Singh; Bevra H. Hahn


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
358 KB
Volume
34
Category
Article
ISSN
0014-2980

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Natural killer T (NKT) cells and CD5(+)B cells were searched for in various immune organs of autoimmune prone (NZBxNZW)F(1) (NZB/W F(1)) mice. The number of lymphocytes increased in the liver, spleen, and peritoneal cavity after the onset of disease (at the age of 30 weeks) while the number of thymo