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Heterotropic Modulation of the Protease-Inhibitor-Recognition Process : Cations Effect the Binding Properties of α-Chymotrypsin

✍ Scribed by Evandro Fioretti; Mauro Angeletti; Giulio Lupidi; Massimo Coletta


Book ID
115130506
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
703 KB
Volume
225
Category
Article
ISSN
1432-1327

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Effect of inhibitor complex formation on
✍ Madeleine Lüscher; Paul Schindler; Max Rüegg; Max Rottenberg 📂 Article 📅 1979 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 908 KB

The effect of enzyme-inhibitor complex formation on the hydration properties of the macromolecular moiety was investigated on the model system of a-chymotrypsin and its Ser-195 tosyl derivative. The primary (A-shell) hydration of the native and modified enzyme was compared by sorption measurements.