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HETEROGENEITY OF MESSENGER RNA DEFECTS IN THE THALASSEMIA SYNDROMES

✍ Scribed by Edward J. Benz; Jonathan Glass; George A. Tsistrakis; Diane G. Hillman; Cesira Cavallesco; Elaine Coupal; Bernard G. Forget; Patricia A. Turner; Judith A. Kantor; Arthur W. Nienhuis


Book ID
118718582
Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
613 KB
Volume
344
Category
Article
ISSN
0890-6564

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Heterogeneity of the Ξ±-globin gene defec
✍ E. -U. Griese; Elisabeth Kohne; J. Horst πŸ“‚ Article πŸ“… 1985 πŸ› Springer 🌐 English βš– 404 KB

Analysis of alpha-thalassemia syndromes in several German families revealed DNA deletion as well as non-deletion forms as the molecular basis for the defects. Thus, the alpha-thalassemia haplotype was identified as the (-alpha)3.7 rightward deletion form, and the region of the putative recombination