Heterogeneity of 125I-labeled human thyroglobulin preparations
β Scribed by Carole A. Spencer; Barbara W. Platler; Richard B. Guttler; John T. Nicoloff
- Book ID
- 115825195
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 836 KB
- Volume
- 151
- Category
- Article
- ISSN
- 0009-8981
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π SIMILAR VOLUMES
Amiloride and certain of its derivatives are effective inhibitors of Na/H antiporters and of epithelial Na channels. We describe a simple method for the preparation of a variety of pharmacologically active 6-iodoamiloride derivatives that are labeled with 125I at high specific radioactivity. 6-Dechl
Iodine-125 labeled spiroperidol has been synthesized by a simple, one-step procedure starting from spiroperidol. and H202 in buffered acetic acid. reaction affords iodospiroperidol in 40% radiochemical yield and a specific activity, after HPLC purification, of ca. 1900 Ci/mmol.