Heterogeneity in Radiation-Induced DNA Damage and Repair in Tumor and Normal Cells Measured Using the "Comet" Assay
✍ Scribed by Peggy L. Olive, Judit P. Banáth and Ralph E. Durand
- Book ID
- 120013728
- Publisher
- Bioone
- Year
- 1990
- Tongue
- English
- Weight
- 822 KB
- Volume
- 122
- Category
- Article
- ISSN
- 0033-7587
- DOI
- 10.2307/3577587
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Stromal cell progenitors (fibroblastoid colony-forming unit; CFU-Fs) are representative of the progenitor cell population of the hemopoietic microenvironment in bone marrow (BM). Previous studies of the radiation dose-effect relationships for colony formotion have shown that canine CFU-Fs are relati
The comet assay was used to measure DNA dam-DNA damage was removed in 2 hr, even in the age and repair in nuclei released from 1 cm root presence of 3-aminobenzamide. Complete repair ends of Vicia faba after X-ray irradiation. Irradia-was inhibited by incubation on ice (30% of DNA tion induced a lin