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Heteroduplex Heterozygotes in Bacteriophage T4 Involving Mutations of Various Dimensions

โœ Scribed by John W. Drake


Book ID
123647208
Publisher
National Academy of Sciences
Year
1966
Tongue
English
Weight
808 KB
Volume
55
Category
Article
ISSN
0027-8424

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A hotspot for transition mutations in th
โœ Singer, Britta Swebilius ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Springer ๐ŸŒ English โš– 729 KB

We have previously demonstrated that the sequence 5'TGGCAA 3' located at codons 32-33 of the rIIB gene of bacteriophage T4 is a hotspot for transition mutations (Nelson et al. 1981). Here I report the properties of the same TGGCAA sequence introduced into the gene at codons 11-12. The sequence is hi