Heterocycles of biological importance. Part 2. Novel synthesis and pharmacological evaluation of 5-amino-3-alkyl-1-(2-pyridyl)pyrazoles and 5-amino-3-phenyl-1-(2-pyridyl)pyrazole from allenic or acetylenic nitriles and 2-hydrazinopyridine
โ Scribed by Z. Tanee Fomum; P. Ngozi Ifeadike
- Book ID
- 112128057
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1985
- Tongue
- English
- Weight
- 254 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0022-152X
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๐ SIMILAR VOLUMES
## Abstract magnified image A series of novel title compounds have been designed and synthesized by a multiโstep reaction, the stereochemistry of the reaction was investigated, the structures of all compounds prepared have been confirmed by ^1^H NMR, IR, EIโMS spectroscopy and elemental analysis.
## Abstract Novel __N__โsubstitutedโ3โaminoโ5โoxoโ4โphenylโ2,5โdihydroโ1__H__โpyrazoleโ1โcarbothioamide derivatives were synthesized by means of two methods. First is the cyclization reaction of 1โ(cyanophenyl)acetylโ4โsubstituted thiosemicarbazide, and the second one is reaction of cyanophenyl ace