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Herpesvirus panencodes a functional homologue of BHRF1, the Epstein-Barr virus v-Bcl-2

✍ Scribed by Melanie Howell; Tracey Williams; Sheila A Hazlewood


Book ID
115005513
Publisher
BioMed Central
Year
2005
Tongue
English
Weight
569 KB
Volume
5
Category
Article
ISSN
1471-2180

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The Epstein-Barr virus (EBV) open reading frame BHRF1, a homologue of the oncogene bcl-2, was cloned from a patient with nasopharyngeal carcinoma (NPC) and overexpressed in Escherichia coli. The resulting recombinant BHRF1 fusion protein, with an apparent molecular weight of 35 KD, was used as antig