Herpesvirus-like DNA sequences in non-Kaposi's sarcoma skin lesions of transplant patients
β Scribed by S.K. Tyring; T.K. Hughes; P.L. Rady; Yen; I. Orengo; J.L. Rollefson; S. Bruce
- Book ID
- 118559560
- Publisher
- The Lancet
- Year
- 1995
- Tongue
- English
- Weight
- 284 KB
- Volume
- 345
- Category
- Article
- ISSN
- 0140-6736
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## Abstract Kaposi's sarcoma (KS) accounts for more than 15% of AIDSβrelated malignancies. The etiology of KS is unresolved but is postulated to be multiβfactorial, involving viruses and overexpression of cellular growth factors and/or oncogenes. Recently, herpesvirusβlike sequences (KSHV) were ide
Kaposi's sarcoma (KS) is a malignancy suspected of having an infectious etiology. Unique viral DNA sequences were recognized in KS lesions, using a novel technique that identifies small differences between two complex genomes. The virus had homology with the herpesvirus family, especially Epstein Ba