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Herpes simplex virus oncolytic vaccine therapy in melanoma

โœ Scribed by Sivendran, Shanthi; Pan, Michael; Kaufman, Howard L; Saenger, Yvonne


Book ID
118039237
Publisher
Informa plc
Year
2010
Tongue
English
Weight
236 KB
Volume
10
Category
Article
ISSN
5847-4714

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## SUMMARY Oncolytic viruses infect, replicate in and kill cancer cells. HSV has emerged as a most promising candidate because it exerts a generally moderate pathogenicity in humans; it is amenable to attenuation and tropism retargeting; the ample genome provides space for heterologous genes; speci