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Hereditary spherocytosis associated with deletion of human erythrocyte ankyrin gene on chromosome 8

✍ Scribed by Lux, Samuel E.; Tse, William T.; Menninger, Joan C.; John, Kathryn M.; Harris, Peter; Shalev, Oded; Chilcote, Robert R.; Marchesi, Sally L.; Watkins, Paul C.; Bennett, Vann


Book ID
109763969
Publisher
Nature Publishing Group
Year
1990
Tongue
English
Weight
511 KB
Volume
345
Category
Article
ISSN
0028-0836

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We describe a case of spherocytosis in a French child splenectomized at age 10 years. The parents were devoid of any clinical, hematological, or biochemical abnormalities. Following splenectomy, the proposita exhibited a reduction of red cell membrane ankyrin. The variable number of dinucleotide rep