✦ LIBER ✦

Hereditary nonpolyposis colorectal cancer and related conditions

✍ Scribed by Lucci-Cordisco, Emanuela ;Zito, Ilaria ;Gensini, Francesca ;Genuardi, Maurizio

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 109 KB
Volume: 122A
Category: Article
ISSN: 0148-7299
DOI: 10.1002/ajmg.a.20475

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Hereditary nonpolyposis colorectal cance

Hereditary nonpolyposis colorectal cancer

✍ Henry T. Lynch; Jane F. Lynch 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 131 KB 👁 2 views

Hereditary nonpolyposis colorectal cancer (HNPCC), or Lynch syndrome, is the most common form of hereditary colorectal cancer (CRC). A well-orchestrated cancer family history is essential for its diagnosis since, unlike its familial adenomatous polyposis (FAP) hereditary cancer counterpart, HNPCC la

Molecular genetics and hereditary cancer

Molecular genetics and hereditary cancer : Hereditary nonpolyposis colorectal carcinoma as a model

✍ Ramon Parsons 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 102 KB 👁 2 views

with the germline mutation of a DNA mismatch repair gene. Tumors from these Departments of Pathology and Medicine, Copatients typically exhibit microsatellite instability, which is a reflection of their lumbia University College of Physicians & Surlack of mismatch repair activity. The genetic diagno

Tumor spectrum in cancer family syndrome

Tumor spectrum in cancer family syndrome (hereditary nonpolyposis colorectal cancer)

✍ J.-P. MecKlin; H. J. Järvinen 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 369 KB 👁 2 views

Clinical manifestations in patients with

Clinical manifestations in patients with hereditary nonpolyposis colorectal cancer

✍ Tomoda, Hirotsugu; Baba, Hideo; Oshiro, Tatsuo 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 408 KB 👁 1 views

The clinical manifestations of 1,042 Japanese patients with nonpolyposis colorectal cancer who underwent a resection between 1972 and 1992 at the National Kyushu Cancer Center were examined. Hereditary nonpolyposis colorectal cancer (HNPCC) was found in 39 (3.7%) patients. Some characteristic findin

Evaluation of enzymatic mutation detecti

Evaluation of enzymatic mutation detection™ in hereditary nonpolyposis colorectal cancer

✍ Robyn Otway; Natasha Tetlow; June Hornby; Maija Kohonen-Corish 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 242 KB 👁 1 views

In hereditary nonpolyposis colorectal cancer (HNPCC), the majority of reported mutations are dispersed throughout the 35 exons of the two principal susceptibility genes, MLH1 and MSH2, and because of this complexity, rapid mutation screening methods are required. The aim of this study was to evaluat

Hereditary nonpolyposis colorectal cance

Hereditary nonpolyposis colorectal cancer: Review of clinical, molecular genetics, and counseling aspects

✍ Bellacosa, Alfonso; Genuardi, Maurizio; Anti, Marcello; Viel, Alessandra; de Leo 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 45 KB 👁 2 views

Lynch syndrome, or hereditary nonpolyposis colon cancer (HNPCC), is an autosomaldominant disease accounting for approximately 1 5 % of all colorectal cancer cases. Due to the lack of pathognomonic morphological or biomolecular markers, HNPCC has traditionally posed unique problems to clinicians and