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Hereditary hemochromatosis in the post-HFE era

โœ Scribed by John K. Olynyk; Debbie Trinder; Grant A. Ramm; Robert S. Britton; Bruce R. Bacon

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
274 KB
Volume
48
Category
Article
ISSN
0270-9139

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โœฆ Synopsis

Following the discovery of the HFE gene in 1996 and its linkage to the iron overload disorder hereditary hemochromatosis (HH) there have been profound developments in our understanding of the pathogenesis of the biochemical and clinical manifestations of a number of iron overload disorders. This article provides an update of recent developments and key issues relating to iron homeostasis and inherited disorders of iron overload, with emphasis on HFE-related HH, and is based on the content of the American Association for the Study of Liver Diseases Single-Topic Conference entitled "Hemochromatosis: What has Happened

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