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Hereditary carcinoma syndromes associated with benign head and neck tumors

โœ Scribed by Dr.; CPT Dale B. Smith; MAJ James E. Arnold; Dr.; MAJ Barbara Fox; Dr.; LTC Don B. Blakeslee

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
466 KB
Volume
11
Category
Article
ISSN
1043-3074

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โœฆ Synopsis

Hereditary forms of carcinoma may be associated with benign head and neck tumors. Many of these hereditary carcinoma syndromes present first to the otolaryngologist. Two unusual cases of Gardner's and Muir-Torre's syndromes illustrate the hereditary carcinoma syndromes associated with head and neck lesions. We describe the use of new genetic markers and propose a diagnostic algorithm. HEAD & NECK 11 :247:251, 1989

Otolaryngologists routinely search for head and neck carcinomas and are aware of the subtleties associated with their diagnosis. They must also be alert to the patient who presents with a benign process in the head and neck, which may signal possible malignancies in other organ systems. A number of hereditary carcinoma syndromes have been described.lP3 Perhaps the most well known of these is Gardner's syndrome. Although mentioned briefly in several otolaryn-

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