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Her-2/neu expression and amplification in early stage ovarian surface epithelial neoplasms

โœ Scribed by Yun Wu; Robert A. Soslow; David S. Marshall; Mario Leitao; Beiyun Chen


Book ID
113959553
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
148 KB
Volume
95
Category
Article
ISSN
0090-8258

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Background. It is unclear whether HER-O/neu proto-oncogene expression in ovarian epithelial neoplasms is related to prognosis. Methods. The authors performed immunohistochemical stains on 20 serous tumors of low malignant potential (STLMP) in Stages I and I1 and 19 serious carcinomas in the same st

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## Abstract HER 2/__neu__ is an important oncogene in breast cancer, but the prevalence and significance of HER 2/__neu__ gene amplification in colon cancer have been poorly documented. We have evaluated HER 2/__neu__ gene amplification and protein overexpression in a series of colon cancers to ass